Marrying against their parents' will, cousins ​​José Arcadio Buendía and Úrsula Iguarán leave their town behind and embark on a long journey in search of a new home. Accompanied by friends and adventurers, their journey culminates with the founding of a utopian town on the banks of a river of prehistoric stones that they call Macondo. Several generations of the Buendía lineage will mark the future of this mythical people, tormented by madness, impossible loves, a bloody and absurd war, and the fear of a terrible curse that condemns them, without any hope, to one hundred years of loneliness.